Welcome to the night skincare routine! Unlike other night creams that can feel heavy or greasy. Whether you’re dealing with the signs of aging or just looking to give your skin a little extra take care, our Drmtlgy peptide night cream is the perfect choice for a healthier, more youthful-looking complexion.

According to dermatologist Dr. Michele Green, “Nighttime is the restorative time for your skin, so you should give your skin the extra TLC by using a night cream. Night creams address different concerns than daytime moisturizers.”

This night cream is lightweight and absorbs quickly, leaving your skin feeling soft, smooth, and refreshed. It’s perfect for all skin types, including sensitive skin, and can be used nightly as part of your regular skincare routine. It is specially formulated to nourish and rejuvenate your skin while you sleep, so you wake up looking and feeling your best.

Moreover, this rich, luxurious night cream by Drmtlgy not only contains 100% plant-based ingredients, it includes 5 peptides and 3 ceramides which help to tighten the skin, smooth wrinkles and lines, and lock in moisture. [1]

“Night is the best time to treat skin and repair concerns such as water loss, skin aging, and dark spots,” says Howard Sobel, M.D., attending dermatologist and dermatologic surgeon at lenox hill hospital in new york city and founder of sobel skin.

This product improves the texture of your complexion, repairs damage, and protects from harmful UV rays. Peptide night cream by Drmtlgy is a popular anti-aging cream that is very reasonably priced for such a high-quality formula.

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DRMTLGY Peptide Night Cream

DRMTLGY Peptide Night Cream

DRMTLGY Peptide Night Cream is a powerful anti-aging moisturizer that’s packed with nourishing and anti-aging ingredients. It’s one of the best night creams on the market and is a great choice for anyone looking for the perfect night cream to help with signs of aging.

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How Does Drmtlgy Peptide Night Cream Work?

This best night cream is designed with all skin types in mind. More than fifteen restorative, anti-aging ingredients, restore your skin back to hydrated glory. Recent advances in nourishing creams focused on reversing & preventing signs of aging also restoring the barrier function of the skin. [2]

This rich, creamy, peptide and ceramide-concentrated formula immediately improves the look of skin’s hydration, texture, and firmness. “It will remove the common sign of skin aging including fine lines, and hyperpigmentation, and will give a fresh skin layer.” said Dr. Marisa Garshick, a board-certified dermatologist

Drmtlgy’s peptide night cream is a popular anti-aging ingredient cream that, restores your pores and skin again to hydrated glory. This rich, creamy, peptide and ceramide-focused method without delay improves the appearance of pores and skin’s hydration, texture, and firmness.

This peptide night cream is a luxurious product that moisturizes skin at night to address the signs of aging. Moreover, the use of powerful ingredients minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin.

Quick Facts & Features

Safe & Quality Star Pictures
Product Peptide Night Cream
Form Cream
Weight 2.1 Ounce
Safety Fragrance-free, Paraben free, & Gluten free
Age Adult
Skin Type Dry, Oily, Sensitive, Combination skin
  • Boosts Skin Texture
  • Wrinkle Reduction
  • Repairs Damage
  • Decreases Inflammation
  • Hyaluronic Acid
  • Vitamin E
  • Peptides
  • Shea Butter
Price $46.00
Shipping Free
Return Policy 60 Days

What Are the Drmtlgy Peptide Night Cream Ingredients?

Drmtlgy Peptide Night Cream Key Ingredients

These are some of the DRMTLGY peptide night cream primary active ingredients:


Cholesterol helps restore the balance of lipids in the skin, hydrating as well as forming a protective barrier to keep the liquid inside and prevent harmful bacteria from entering. It also boosts the overall health and appearance of the complexion. [3]

The added moisture plumps the skin and smooths fine lines and wrinkles. An article in the Journal of Lipid Research discussed the key role lipid metabolism plays in skin health.

Shea Butter

This very moisturizing fatty substance comes from the African Shea tree, and it both provides deep hydration to the skin and eliminates dryness. It’s very high in anti-inflammatory agents and could soothe and heal certain skin conditions. [4].

It also contains antioxidants that repair skin damage and protect from UV rays. An article in the Journal of Biology, Agriculture, and Healthcare discussed the nutritional and medicinal properties of the shea tree.


As chains of amino acids, the 5 peptide strains included in this cream have the ability to stimulate a large amounts of collagen and elastin, which tightens the complexion, improves elasticity, and smooths fine lines and wrinkles.[5]

Peptides are a harmless ingredient that generally won’t negatively affect you, explained Dr. Susan Massick, board-certified dermatologist at the ohio state university.

Peptides also have antioxidant potential and can help improve the health and immunity of the skin, repair, and protect from damage. A review of the research in the International Journal of Cosmetic Science examined the anti-aging benefits of peptides for the skin.


These are lipids that are a natural part of the skin, making up a quarter or more of the outer layer of the epidermis. They provide moisture and also form a protective barrier that keeps the liquid locked in while keeping out germs and bacteria. [6].

Ceramides are very important lipids that are naturally found within our body, which help to maintain the integrity of the skin barrier and hold hydration in the skin,” says Dr. Alexis Stephens, Board-certified dermatologist

This extra liquid plumps the skin, which may help smooth wrinkles and fine lines. A review of studies in the American Journal of Clinical Dermatology found that ceramides play a beneficial role in improving barrier function.

Tocopherol (Vitamin E)

A strong antioxidant like Vitamin E works to shield the skin from free radical damage and delay the onset of premature aging. Moreover, it can aid in soothing and moisturizing dry, sensitive skin.[7].

A research review by the International Institute of Health investigated the anti-aging effects of Vitamin E on the skin. Scientists are investigating whether, by limiting free-radical production and possibly through other mechanisms, Vitamin E might help prevent or delay the chronic diseases associated with free radicals.


One of the best ingredients for moisturizing and calming the skin is glycerin. It hydrates and moisturizes the skin by drawing water to it and keeping it there.

Glycerin is a one of the greatest ingredients for dry skin types, according to popular Belif Moisturizing Eye Bomb.

A deep research of safety assessment of glycerin as used in cosmetics for glycerin as used in cosmetics. The Panel concluded that glycerin is safe as a cosmetic ingredient in the practices of use and concentration described in this safety assessment.


Phytosphingosine, a lipid that is naturally present in the skin, is a really pleasant addition to this moisturizer. It aids in restoring the skin’s natural barrier, shielding it from irritants outside, and maintaining a moisture seal. It has also been demonstrated to possess antibacterial qualities. [9].

An expert conducted research in a science direct journal for phytosphingosine via the action of ceramide synthase yielding ceramide, dihydroceramide, and phytoceramide, respectively.

drmtlgy peptide night cream

“Drmtlgy Peptide Night Cream Reviews. Image by GorgeousGirl”

Drmtlgy Peptide Night Cream Pros & Cons

  • The cream is free of fragrance, oil, parabens, sulfates, and gluten.
  • Peptide Night Cream by Drmtlgy can hydrate the complexion and eliminate dryness.
  • This formula can smooth wrinkles and fine lines on the skin.
  • Peptide Night Cream can enhance skin texture.
  • It can repair damage to the skin barrier.
  • The manufacturer is 100% cruelty-free.
  • Results will vary for different individuals.
  • This is a popular product that may sometimes run low on stock.
  • There are other ingredients they could include.

What Do the Drmtlgy Peptide Night Cream Reviews Say?

Here are some of the top reviews, so you can see what customers are saying about this amazing night cream.

In Love

Love the Peptide Night Cream. It feels amazing. Have used it on my arms, chest, and hands as well. Notice a difference anywhere it goes! – Mary

Perfect Moisturizer

Have been using the product for over 30 days now. It is very light and feels amazing on the skin. Perfect amount of hydration – Linda J.

Thick Night Cream

Typically used the same moisturizer for am and pm but wanted to give this a try since there are now more actives in my routine and could use extra hydration at night.

This cream is pretty thick and goes on like a lotion, but it slowly absorbs all night and skin is very moisturized in the morning. If you have really dry skin or live in a cold climate this would make a good daytime moisturizer as well. – Barbara L.

Perfect For So Many Reasons

This is such a perfect moisturizer. It’s versatile and you can use it at night or during the day. It has added hydration when you need it, it’s so gentle and plays nicely with other products.

It’s somehow light enough to absorb completely but makes the skin feel completely hydrated and not wanting for more. Definitely repurchasing and will continue to try more products because they’ve all been amazing so far and great price points. – PATRICIA C.

Best Night Moisturizer

This is the best night time moisturizer I’ve ever tried. First all it doesnt leave you greasy at all, which is uncommon in all the brands I’ve tried. It is unscented, absorbs quickly and a little goes a long ways. Highly recommend if your looking for a new night cream! Jenni James

The Evidence Score

  • Improve Appearance in Skin’s Smoothness4.5/5
  • Strengthens Skin Barrier4.6/5
  • Long-Lasting4.0/5
  • Targets Fine Lines and Wrinkles4.7/5
  • Boosts Elasticity & Collagen Performance4.5/5
  • Healthy Aging4.3/5

Related-Rodan and Fields Redefine Night Renewing Serum


How Much Does Drmtlgy Peptide Night Cream Cost?

A: Peptide Night Cream is for sale on the manufacturer’s official website, as well as from several other online retailers.

On the official site, you can make a one-time purchase for $46, or subscribe and save for $37. If you click the link at the top of the page, they’ll send an additional 20% off to your phone.

Place Your Order, Visit the official website

Is This Product Recommended for Purchase?

A: Drmtlgy is a highly reputable brand that produces quality, safe, 100% organic skin care products which are gentle for the complexion and suitable for all skin types.

Peptide Night Cream is among their best products, with very positive reviews from customers in general. This formula also comes highly recommended by dermatologists worldwide.

Does Drmtlgy Peptide Night Cream Come With A Guarantee?

A: Drmtlgy is offering a 60-day return policy for the brand. If you’re not happy with this cream, get in touch with customer service for return instructions. Then send the product back within 60 days of the purchase. You should get a full refund, minus the return shipping costs.

What Are the Side Effects?

A: This cream contains 100% natural ingredients which are safe and free of parabens, sulfates, fragrance, and gluten. It’s suitable for all skin types including sensitive and should not cause side effects or skin irritation.

Who Should Use It?

A: This cream is ideal as the best eye cream for dark circles and wrinkles who have dull skin and want to remove their skin barriers and eliminate some of the signs of age.

Peptide Night Cream is also an excellent moisturizer and complexion-boosting formula for younger users who want to slow aging and preserve their skin for as long as possible.

Does Drmtlgy Peptide Night Cream Really Work?

A: The formula includes powerful peptides which stimulate collagen and elastin production. This leads to tighter skin with improved skin elasticity. It provides maximum hydration and anti-aging benefits.

It doesn’t contain any harsh alcohols, common allergens, oils, parabens, or sulfates. A rich, creamy nighttime moisturizer that adds layers of hydration to help soften the appearance of signs of aging and repair damaged skin.

“Night creams are going to help with wrinkles, fine lines, and exfoliation,” says Dr. Kelly Swanson, a physician’s assistant based in clarkson

How is it Unique From the Competition?

A: This is a very high-quality formula on the level of luxury cream, yet it does not have a luxury price tag. The ingredients are safe, scientifically backed, suitable for all skin types, and vegan. The company is very well-known and highly regarded.

Do Night Creams Really Work?

A: When collagen is low, wrinkles and fine lines are more noticeable. Your skin will appear plumper and firmer as a result of using a night cream, which increases collagen production. This minimizes sagging and the visibility of wrinkles and fine lines. Your skin’s suppleness is, in other words, given a much-needed boost.

Can We Use Night Cream Daily?

A: In most cases, it is safe to use a night cream every other night. But again, it depends on the ingredients in the night cream and your skin type. Using a night cream during the day leaves your skin more susceptible to sun and environmental damage because it lacks protective ingredients.

What Is the Side Effect of Night Cream?

A: The majority of moisturizers can be used without risk and with great success. However, it’s possible to feel burning, stinging, redness, or irritation. Inform your doctor or chemist as soon as possible if any of these side effects persist or get worse.

Does Night Cream Make You Look Younger?

A: To treat skin issues like lines, wrinkles, and dark spots, night creams are brimming with potent anti-agers and skincare chemicals. Over time, this results in a more hydrated, youthful-looking face.

What Is Night Cream Used For?

A: Night creams help soothe and soothe the skin throughout the night, allowing redness and irritation to disappear while you sleep. This will help even out your skin tone in the morning. Acne and breakouts can dry out your skin. However, it should also be soothing and moisturizing.

What is the Drmtlgy Peptide Night Cream Return Policy?

A: This manufacturer offers a generous 60-day return policy. If you are not satisfied with your purchase, please contact our Customer Service Department for instructions and return the product within 60 days of purchase. You must receive a full refund, but you are responsible for the return shipping costs.

Where to Buy Peptide Night Cream?

A: This peptide-based night cream is available from the manufacturer’s official website and many other online retailers such as amazon.

It costs $46.00 on the official site if you make a one-time purchase, and 37% if you subscribe. If you click on the top link, you can get an extra 20% off sent to your mobile.

Feature Competitor Product Comparison

Drmtlgy CeraVe Skin Renewing Drunk Elephant Skinfix Barrier+
Product Images qualia-mind qualia-mind qualia-mind qualia-mind
Lowest Possible Price $79.00 per serving $15.87 per serving $32.00 per serving $54.00 per serving
Product Safety Non-greasy, Non-comedogenic Fragrance-free Cruelty-free Vegan
Concerns It won’t be harmful to the skin Might be harmful sometimes May cause a skin reaction May be more susceptible to irritation
Notable Ingredients Rating 92% are liked 86% are liked 74% are liked 87% are liked

Drmtlgy Peptide Night Cream Before and After – See Real Results

DRMTLGY Peptide Night Cream Before and After ImagesDRMTLGY Peptide Night Cream Before and After Images

Final Thought

drmtlgy peptide night cream guarantee image

Peptide Night Cream by Drmtlgy is an anti-aging, deeply moisturizing cream that hydrates your complexion at night as you sleep, replacing lost collagen and elastin, tightening, and smoothing wrinkles, fine lines, and other signs of age. Many high-level dermatologists recommend this formula.

The vast majority of the reviews for Peptide Night Cream raved about the amazing moisturizing and anti-aging properties of this product. Users also said it absorbed fast, wasn’t greasy, and felt soothing when they applied it at night before bed.

This cream contains 100% pure, organic ingredients which are scientifically backed, third-party tested for quality and safety, and free of fragrance, parabens, sulfates, and gluten. It should not lead to harmful side effects or skin irritation.

Where to Find It?

Place Your Order, Visit Official Website

9 sources

At GorgeousGirl, we only use primary references for our articles, including peer reviewed medical journals or well-respected academic institutions.

[1] Spada F, Barnes TM, Greive KA. Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems. Clin Cosmet Investig Dermatol. 2018 Oct 15;11:491-497. doi: 10.2147/CCID.S177697. PMID: 30410378; PMCID: PMC6197824. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197824/
[2] Del Rosso JQ. Repair and maintenance of the epidermal barrier in patients diagnosed with atopic dermatitis: an evaluation of the components of a body wash-moisturizer skin care regimen directed at management of atopic skin. J Clin Aesthet Dermatol. 2011 Jun;4(6):45-55. PMID: 21779416; PMCID: PMC3140899. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140899/
[3] Spada F, Barnes TM, Greive KA. Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems. Clin Cosmet Investig Dermatol. 2018 Oct 15;11:491-497. doi: 10.2147/CCID.S177697. PMID: 30410378; PMCID: PMC6197824. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197824/
[4] Shea Butter: https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/shea-butter
[5] Jeong S, Yoon S, Kim S, Jung J, Kor M, Shin K, Lim C, Han HS, Lee H, Park KY, Kim J, Chung HJ, Kim HJ. Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression. Int J Mol Sci. 2019 Dec 20;21(1):73. doi: 10.3390/ijms21010073. PMID: 31861912; PMCID: PMC6981886. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981886/
[6] Meckfessel MH, Brandt S. The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products. J Am Acad Dermatol. 2014 Jul;71(1):177-84. doi: 10.1016/j.jaad.2014.01.891. Epub 2014 Mar 20. PMID: 24656726. https://pubmed.ncbi.nlm.nih.gov/24656726/
[7] Keen MA, Hassan I. Vitamin E in dermatology. Indian Dermatol Online J. 2016 Jul-Aug;7(4):311-5. doi: 10.4103/2229-5178.185494. PMID: 27559512; PMCID: PMC4976416. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976416/
[8] Safety Assessment of Glycerin as Used in Cosmetics https://journals.sagepub.com/doi/full/10.1177/1091581819883820
[9] Phytosphingosine https://www.sciencedirect.com/topics/chemistry/phytosphingosine

By Gorgeousgirl Staff

At GorgeousGirl, our staff is a collection of highly skilled cosmetologists, estheticians, and higher education professionals. Our personnel works together to satisfy your fancies.

Average Customer Rating:4.0 / 5.0 
1 Customer Reviews

Rating Snapshot:

Write a Review You can receive 50 rewards points by sharing your honest opinion of Drmtlgy Peptide Night Cream Write a Review
    Diana Diamond

    I use this cream for the last 2 weeks it is incredibly well and lovely. This is a fast-absorbing and long-term effective skincare cream.


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